@foone what are you wanting to output from them? they have hardware decoders for a bunch of codecs. I vaguely recall MPEG2 and VC1 need a licence code (or other means) but MPEG4 was standard. Later Pi's don't have MPEG2 or VC1 at all.
If you're wanting lossless - yeah, Huffyuv is probably the way to go. but you'll have a YUV -> RGB -> YUV conversion which might introduce some quality loss.