It’s very cool that Bluefin have managed to get homebrew working in an rpm-ostree environment without conflicting with host paths.
https://universal-blue.discourse.group/t/bluefin-is-feature-complete/703
I always thought homebrew would be perfect for atomic Linux but ran into the same issues. Today, I run Rust-based CLI apps installed with cargo and/or, less favourably, Go apps. I only use a container when I have to build something from source.
So, yeah, I’ll be keeping an eye on Bluefin. They seem to get it.