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1. Barry Solow (baslow@friendica.communitarium.org)'s status on Tuesday, 22-Aug-2023 14:31:23 JST Barry Solow
   Long-Term Long Covid
   
   open.substack.com/pub/erictopo…
   New reports at two years and the known unknowns that lie ahead
   
   At two years after Covid, there’s a persistent and considerable burden of symptoms and multi-system organ involvement in an important subgroup of people. It’s also unpredictable who will be afflicted with protracted symptoms and new medical diagnoses. While there still is no validated treatment (the Big Miss, as recently reviewed), Long Covid marches on, not just over time for most of those already suffering, but also among newly infected or re-infected individuals —like we are seeing now with increase in cases in the United States and many other countries. The main emphasis here, beyond the enduring and very concerning symptoms and organ dysfunction, is that we are still in the dark. It will take many years to fully know the sequelae of Covid, be it from unforeseen, delayed adverse outcomes like what occurred many years after influenza or polio, or the secondary outcomes of organ systems that are clearly affected, or via promotion of autoimmune conditions or pro-inflammatory pathways, potentially exacerbating risk of atherosclerosis. We’re going to need many more years of careful follow-up to fully understand the ways and extent Covid has hurt us. Meanwhile, beyond the known strategies for prevention of infection, we must consider finding effective ways to treat people who suffer from Long Covid as an urgent and foremost priority.
   #Covid
   #LongCovid