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@WashedOutGundamPilot @Tepid_Tapir >They theorize that the possum’s blood temp is too low for incubation. I’d probably blame behavior, possums are wiley.
That seems suspect. Rabies only has to get to a nerve cell and then moves its way across the nerves, slowly replicating up towards the brain as a sort of incredibly slow acting sleeper viral meningitis. This is why rabies can show symptoms anywhere from a handful of days to 6 months later, and sometimes people have no idea how they came into contact with it. I believe the rabies treatment (vaccine) works because it's the old school method of simple exposure to the virus which otherwise you'd never run into in the wild. Keep in mind nerve cells are less exposed to pathogens or the immune system in general, so if it can slip in, it's got a pretty simple ride all the way to the brain. The animal proteins in unpurified primitive vaccines would act as a natural adjuvant to increase response, but primitive vaccines also carried risk of accidental infection with rabies. Funny thing about rabies is it's one of the few diseases where the black box warning on the vaccine sheet say "if you're pregnant or sick, get the vaccine anyways if you're bitten by an obvious rabid animal because you're gonna die."

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